The Uses & Make Up Of Xarelto
Xarelto is a relatively new doctor prescribed blood thinner that was released onto the United States market in 2011. Xarelto, the active drug ingredient being rivaroxaban, is unlike other blood thinners due to it being an Xa inhibitor. Xa inhibitors prevent blood clots by blocking the chemical in the blood that is in charge of making them, Thrombin.
Intense marketing campaigns has helped Xarelto become the leading blood thinner in its class in the United States. It has been prescribed to 11 million people in the U.S. since its release. Xarelto originally received FDA approval to treat several conditions and it is officially approved for a total of six uses:
- Reducing risk of stroke in patients with atrial fibrillation (AF)
- Treatment of Deep Vein Thrombosis (DVT)
- Treatment of Pulmonary Embolism (PE)
- Reduction of recurrence of DVT & PE
- Prevention of DVT in knee replacement surgery
- Prevention of DVT in hip replacement surgery
Even though the drug has seen success in the market, since its release several studies have been published that link the drug to very concerning negative effects some of which include profuse internal bleeding that is impossible to control leading to severe injury or even death.
Xarelto’s Dangerous Side Effects
The most commonly reported adverse events associated with Xarelto usage are Pulmonary embolism, deep vein thrombosis, gastrointestnial bleeding and brain bleeding. The former are caused when patients prematurely stop Xarelto usage and the latter are caused by uncontrollable internal bleeding.
Serious Internal Bleeding
Xarelto can cause serious, uncontrollable internal bleeding because the drug lacks a reversal antidote like other blood thinners do. If a patient is prescribed a blood thinner such as Warfarin, under critical circumstances a doctor can give them vitamin K or protamine sulfate and reverse the anticoagulant effects of the drug. With Xarelto, there is no such corresponding reversal antidote. If a patient taking Xarelto suffers a fall or another injury that causes internal bleeding, there is no know method to cease it. Internal bleeding is often difficult to diagnose and hard to spot until it leads to a bigger problem. This uncontrollable internal bleeding can lead to very serious injuries, especially if the bleeding takes place in the abdomen or the brain, where there is a very high concentration of vital organs that could be cut off from their oxygen supply if blood pools around them.
Excessive Blood Clots
If someone using Xarelto prematurely discontinues usage of the drug, they are putting themselves in danger of excessive blood clots and serious complications as a result. This commonly happens when a patient stops taking Xarelto to transition over to another blood thinner. Ceasing Xarelto usage suddenly can cause deep vein thrombosis, a condition where blood clots form in the deep veins of the arms or the legs and then travel to other parts of the body where they can cause blockages. A pulmonary embolism is when these blood clots travel to the lungs and cause a blockage there. Pulmonary embolisms are extremely serious because they are difficult to detect and once symptoms begin to present themselves, damage may already have been done. For more information on Xarelto’s side effects, visit our Xarelto Side Effects page here.
Xarelto Drug Interactions
In early 2014, the FDA issued a warning that listed several medications that it is not advised or safe to take Xarelto with. Doing so could cause unexpected side effects and potentially cause serious injury. The complete list of medications is below:
- Itraconazole – Sporanox and Onmel
- lopinavir – Kaletra
- Ritonavir – Norvir
- Indinavir – Crixivan
- Conivaptan – Vaprisol
- Carbamazepine – Tegretol, Tegretol-XR, Equetro, Carbatrol, Epitol, and Teril
- Phenytoin – Dilantin
- Rifampin – Rifater, Rifamate, Rimactane, and Rifadin
- St. John’s wort – Hypericum Perforatum
Xarelto Injuries in Rhode Island
At Blood Thinner Help we have been able to utilize established information in order to know the statistics of Xarelto related injuries in Rhode Island. By comparing the population of Rhode Island as of the recorded 2010 U.S. Census to the total Xarelto prescriptions that have been written in America, we are able to estimate the number of people who have taken Xarelto in Rhode Island and then how many people may have been injured by Xarelto in Rhode Island’s most populous cities.
As of the 2010 U.S. Census, Rhode Island had a population of 1,052,567. We estimate that 637 residents of the entire state of Rhode Island may have experienced internal bleeding incidents after taking Xarelto. Here is the data for Rhode Island’s top five largest cities:
Rhode Island’s Most Populous Cities
- Providence – 178,042
- Warwick – 82,672
- Cranston – 80,387
- Pawtucket – 71,148
- East Providence – 47,037
Estimated Number of Xarelto Injuries
- Providence – 108
- Warwick – 50
- Cranston – 48
- Pawtucket – 43
- East Providence – 28
Filing a Xarelto Lawsuit?
If you or someone close to you have experienced any of the side effects listed above, you may have a case against Xarelto and its manufacturers. Cases against Xarelto are currently being filed across the country and are being consolidated into a Multidistrict Litigation in New Orleans, Louisiana.
Our Xarelto attorneys at Blood Thinner Help are authorized to practice law in Pennsylvania, New Jersey, Virginia, Washington D.C and Massachusetts, but through our work on Xarelto cases we have developed excellent working relationships with lawyers in every state who have the experience and skills necessary to take Xarelto cases. We would be happy to refer you to a lawyer locally who could take your case. Get in touch with us here for a free of charge appointment and case evaluation and we will be happy to answer any questions you may have and discuss your legal options.