The drug Xarelto was originally authorized by the Food and Drug Administration for use in reducing the risk of blood clots in patients who have undergone hip or knee replacement surgery. The drug, also known as Rivaroxaban, was also approved for the prevention of coagulation in patients suffering from atrial fibrillation. Atrial fibrillation or Afib, is known as a quivering or irregular heartbeat that can cause blood clots and various heart related problems.
What Does Xarelto Do?
As a blood thinner or anticoagulant, Xarelto contains an active ingredient rivaroxaban which is an Xa inhibitor, meaning it obstructs Thrombin. Thrombin is an enzyme that presides in the conversion of fibrinogen to fibrin, promoting blood clotting. Preventing blood clots is exactly what is necessary for patients taking blood thinners. The danger in this scenario is when an injury occurs and the blood does not clot. Xarelto inhibits wounds from healing due to its ability to prevent the blood from clotting. This can result in extensive unmanageable internal bleeding.
Can Internal Bleeding Be Stopped?
This question is likely to be raised, because as with any blood thinner, there is the risk of internal bleeding. This is correct, however, when it comes to Xarelto the risk of internal bleeding is significantly increased because there is no way to reverse the effects of the medication. For example, if a patient is taking the blood thinner Warfarin, the effects of the medication can be reversed if an injury occurs by administering Vitamin K or protamine sulfate which help with blood clotting. In the case of Xarelto, the fact that it blocks thrombin prevents known reversal antidotes from being effective, therefore putting the patients already taking Xarelto in grave danger if they suffer an injury that leads to internal bleeding.
Although the FDA originally approved Xarelto, it has not recalled the drug but has issued several important safety communications about the drug and also issued two ‘black box warnings’. A black box warning is the most stringent warning the FDA can give to a drug. Some of the FDA Xarelto warnings are as follows:
- August 2013, a black box warning was issued stating that patients who abruptly stopped taking Xaretlo were at greater risk of blood clots and epidural/spinal hematoma.
- January 2014, a cautionary warning against Xarelto was given stating that the FDA was aware of there being a risk of bleeding in patients taking Xarelto. Patients were advised to have blood transfusions or blood replacement if they had blood loss symptoms. The FDA also revealed that there was no reversal agent or antidote for Xarelto.
- March 2014, the strictest FDA warning was issued by the FDA with legitimate evidence that Xarelto was the cause of serious injury in patients who were undergoing an epidural (anesthesia) or spinal puncture. The warning stipulated that if someone taking Xarelto needed such a procedure and was taking Xarelto, they needed to wait until the drug was out of their system.
- In 2014 the FDA issued a warning with a list of medication that must not be taken in conjunction with Xarelto because the combination could be fatal. For a list of the medications click here.
Kansas: Internal Bleeding Statistics
From the time Xarelto was authorized for use in 2011, more than 11 million prescriptions have been written for the drug all over the United States. Utilizing known data of the United States population since the last census, with a combination of the sum of Xarelto prescriptions in the U.S. as well as the Kansas population and its five most populous cities, we have calculated the potential number of internal bleeding incidents that may have transpired in Kansas since Xarelto came on the market.
The latest Kansas population estimate was 2,904,021 therefore, we calculated an estimated 1,702 Kansas internal bleeding incidents. Here is the data broken down by city:
Population of the Five Major Cities In Kansas
- Wichita- 388,413 population
- Overland Park- 184,525 population
- Kansas City- 149,636 population
- Olathe- 133,062 population
- Topeka- 127,215 population
Internal Bleeding Incidents in Kansas’ Most Populated Cities
- Wichita- 228
- Overland Park- 108
- Kansas City- 88
- Olathe- 78
- Topeka- 75
Contacting Xarelto Lawyers
The effects of Xarelto are devastating. If you or a loved one, residing in Kansas, took Xarelto and suffered any of the adverse events mentioned above contact us, we are here to answer any questions you most likely have at this stage. In addition, we offer free consultation and case evaluation. Our lawyers are here to help you at any time and will answer any question you may have.
Your case is in good hands with our Kansas Xarelto lawyers. Our lawyers have the experience necessary to take on large pharmaceuticals as well as many years of experience dealing with this kind of law.
Where To Seek Help If You Are A Kansas Xarelto Victim
There are numerous hospitals in and around Kansas where you can seek help if you suspect any adverse effects from taking Xarelto. If you suspect something is wrong, don’t delay get medical help immediately. Below are two of the best hospitals you can seek medical attention from immediately:
University Of Kansas Hospital
3901 Rainbow Boulevard
Kansas City, KS 66160-7200
Via Christi Hospital St.Francis
929 North St Francis Street
Wichita, KS 67214-3882