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Recent Xarelto News

Xarelto Lawsuits in Philadelphia For Internal Bleeding

Xarelto: A New Class Of Prescription Blood Thinner

Xarelto is a prescription anticoagulant that was approved by the Food and Drug Administration (FDA) in 2011.  This blood thinner contains the active ingredient rivaroxaban, an Xa inhibitor that blocks a part of the blood called Thrombin.

Thrombin is what makes blood clot and by blocking it, Xarelto prevents the blood from doing so.  This is a good thing for most patients who are taking blood thinners, such as patients who have recently had a hip or knee replacement surgery or for patients who are experiencing excessive blood clots from other medical issues.

xarelto lawsuits in philadelphia

This was the intent that Xarelto was manufactured with but since its release onto the market Xarelto has shown to be a dangerous drug with severe side effects that can cause massive internal bleeding and death.

Why Should I Be Concerned About Xarelto?

Internal bleeding is a risk with all blood thinners, but Xarelto is especially dangerous because there is no reversal antidote for the medication.  In the event of a severe injury, the effects of other blood thinner medications, such as Warfarin, can be reversed if need be with Vitamin K or protamine sulfate – both of which help the blood to clot.  If an individual taking Xarelto suffers an injury that causes internal bleeding, there is no antidote to reverse the effects of Xarelto.  Since Xarelto blocks Thrombin, the antidotes that work with other blood thinners will not work with Xarelto.

Xarelto currently has two ‘Black Box’ warnings attached to it by the FDA.  The Black Box warnings are the strictest warnings the FDA can assign to a drug short of recalling it. When a drug receives a black box warning it usually means that there is ‘reasonable evidence’ of a hazard associated with taking the drug.  Individuals taking Xarelto were also warned by the FDA that if they prematurely discontinued taking the medication, they were at a much higher risk of blood clots, deep vein thrombosis, and epidural or spinal hematoma.

The FDA also issued another warning in 2014 listing medications that should not be taken with Xarelto and could potentially cause harm if done so.  The medications are listed here:

  • Itraconazole – Sporanox and Onmel
  • lopinavir – Kaletra
  • Ritonavir – Norvir
  • Indinavir – Crixivan
  • Conivaptan – Vaprisol
  • Carbamazepine – Tegretol, Tegretol-XR, Equetro, Carbatrol, Epitol, and Teril
  • Phenytoin – Dilantin
  • Rifampin – Rifater, Rifamate, Rimactane, and Rifadin
  • St. John’s wort – Hypericum Perforatum

Xarelto Side Effects

Xarelto is known to cause many adverse events in individuals taking the medication and most of these adverse events are usually caused by Xarelto’s most dangerous side effect; uncontrollable internal bleeding.  Since the blood cannot clot in an individual taking Xarelto and there is no known antidote, if the individual suffers from even the slightest injury to cause internal bleeding the effects can be catastrophic. Internal bleeding can cause blood to pool around organs, cut off their blood and oxygen supply, and damage them or cause them to stop functioning.

The most commonly reported event linked to Xarelto is a pulmonary embolism and the second most commonly reported event is deep vein thrombosis.  Both of these events are caused by blood clots lodging themselves in places where they shouldn’t be, in this case the lungs.  The formation of sudden blood clots is a side effect associated with prematurely stopping Xarelto usage.  The third and fourth commonly reported side effects are gastrointestinal bleeds and hemorrhages, both of these being caused by the irreversible internal bleeding associated with Xarelto.

For more information, visit our Xarelto Side Effects page.

Internal Bleeding Incidents in Philadelphia

Our experts have been able to estimate how many internal bleeding incidents may have occurred in Philadelphia since Xarelto was released.  Since Xarelto was approved by the FDA in 2011, there have been over 11 million prescriptions written across the country.  The next step is to factor in the population of Philadelphia at the time of the last census which was taken in 2010.

Philadelphia Population – 1,553,165

By comparing the population of Philadelphia to the number of prescriptions written for the entire United States and the incident rate of adverse reactions, we can estimate the number of potential adverse reactions to Xarelto in Philadelphia.

Internal Bleeding Incidents in Philadelphia – 941

Our Philadelphia Xarelto Lawyers

Have you experienced any of the side effects or adverse events described in this article while taking Xarelto?  Do you think you may be one of those 941 people who have experienced an adverse reaction?

If so, you may have a legal case against Bayer AG and Johnson&Johnson, and may be entitled to compensation for your pain and suffering.

Our Philadelphia Xarelto Lawyers are experienced in handling large cases against big pharmaceutical companies and are prepared to fight for you.  We are currently accepting cases in the Philadelphia region and across the country.  If you think you have a case against Xarelto, contact us today for a free case evaluation and consultation.

You can reach our Philadelphia Xarelto Lawyers here.  They are available 24/7 to answer your questions.

Resources for Philadelphia Xarelto Victims

If you or a loved one are currently taking Xarelto and think you may be experiencing any of these side effects, it is important that you seek medical attention immediately.  There are many hospitals located across the city of Philadelphia, here are two centrally located ones:

Thomas Jefferson University Hospital
111 S. 11th Street
Philadelphia, PA 19107
(215) 955-6000

Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
(215) 662-4000

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